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https://research.matf.bg.ac.rs/handle/123456789/2738| Title: | T-cell epitope frequency in ordered and disordered protein regions of tumor associated antigens | Authors: | Pavlović, Mirjana Mitić, Nenad Jandrlić, Davorka Beljanski, Miloš |
Issue Date: | 2012 | Rank: | M33 | Publisher: | Beograd : Društvo fizikohemičara Srbije | Related Publication(s): | Physical Chemistry 2012 : Proceedings of 11th International Conference of Fundamental and Applied Aspects of Physical Chemistry | Conference: | International Conference on Fundamental and Applied Aspects of Physical Chemistry (11 ; 2012 ; Belgrade) | Abstract: | Using epitope predictions it was shown that both Human Leukocyte Antigens class I and class II (HLA-I and HLA-II) epitopes were more frequent in ordered regions of proteins and that epitopes appertaining to ordered protein regions were prevalently hydrophobic. The comparison between predicted and experimentally evaluated epitopes of several tumor-associated antigens, revealed that majority of epitopes, presented by HLA-I and HLA-II molecules, are localized in ordered protein regions. |
URI: | https://research.matf.bg.ac.rs/handle/123456789/2738 |
| Appears in Collections: | Research outputs |
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