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https://research.matf.bg.ac.rs/handle/123456789/321
Title: | A structural entropy index to analyse local conformations in intrinsically disordered proteins |
Authors: | Akhila, Melarkode Vattekatte Narwani, Tarun Jairaj Floch, Aline Maljković, Mirjana Bisoo, Soubika Shinada, Nicolas K Kranjc, Agata Gelly, Jean-Christophe Srinivasan, Narayanaswamy Mitić, Nenad de Brevern, Alexandre G |
Affiliations: | Informatics and Computer Science |
Keywords: | Entropy;Flexibility;Protein structures;Rigidity;Structural alphabet |
Issue Date: | 2020 |
Journal: | Journal of structural biology |
Abstract: | Sequence - structure - function paradigm has been revolutionized by the discovery of disordered regions and disordered proteins more than two decades ago. While the definition of rigidity is simple with X-ray structures, the notion of flexibility is linked to high experimental B-factors. The definition of disordered regions is more complex as in these same X-ray structures; it is associated to the... |
URI: | https://research.matf.bg.ac.rs/handle/123456789/321 |
ISSN: | 10478477 |
DOI: | 10.1016/j.jsb.2020.107464 |
Appears in Collections: | Research outputs |
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